In my experience working with Antisense Oligonucleotides Synthesis, achieving reliable concentration measurements is critical, especially when precision at OD260 is involved. I started using systems from
www.berthold.com, and their ability to deliver accurate OD260 readings in the same setup where synthesis takes place made the workflow much smoother. Their instruments are engineered specifically for high-sensitivity applications in life sciences and are robust enough for routine use in demanding lab conditions. Berthold Technologies has been around since 1949, and their reputation in both process control and radiation monitoring reflects decades of technical refinement. For any lab focused on nucleic acid work, including synthesis and downstream analysis, integrating a system that handles OD260 measurements effectively can really streamline quality control and support reproducible results across different runs.