The drivers are loaded, and I can use either dongle with Simulator and AW2, on three different computers including the development one. It just seems to be the release version of the ANTFS Host that I compiled (UI changes such as adding factory reset button and making directory box larger) that shouldn't have changed behavior with USB1.
If nothing else I guess I can swap out a few more USB1s for USB2s until have time to more fully investigate.
PS - not newbie as forum thinks, old log in was nszmnsky